Gene name:
SLC18A2 (SVMT;VMAT2) ;
Protein name:
Synaptic vesicular amine transporter ;
Alternative:
Solute carrier family 18 member 2 ;Monoamine transporter ;Vesicular amine transporter 2 (VAT2) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with SLC6A3.
Function:
Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis.
Subcellular Location:
Cytoplasmic vesicle membrane
Multi-pass membrane protein
Protein Attributes:
50:
MALSELALVR | WLQESRRSRK | LILFIVFLAL | LLDNMLLTVV | VPIIPSYLYS |
100:
IKHEKNATEI | QTARPVHTAS | ISDSFQSIFS | YYDNSTMVTG | NATRDLTLHQ |
150:
TATQHMVTNA | SAVPSDCPSE | DKDLLNENVQ | VGLLFASKAT | VQLITNPFIG |
200:
LLTNRIGYPI | PIFAGFCIMF | VSTIMFAFSS | SYAFLLIARS | LQGIGSSCSS |
250:
VAGMGMLASV | YTDDEERGNV | MGIALGGLAM | GVLVGPPFGS | VLYEFVGKTA |
300:
PFLVLAALVL | LDGAIQLFVL | QPSRVQPESQ | KGTPLTTLLK | DPYILIAAGS |
350:
ICFANMGIAM | LEPALPIWMM | ETMCSRKWQL | GVAFLPASIS | YLIGTNIFGI |
400:
LAHKMGRWLC | ALLGMIIVGV | SILCIPFAKN | IYGLIAPNFG | VGFAIGMVDS |
450:
SMMPIMGYLV | DLRHVSVYGS | VYAIADVAFC | MGYAIGPSAG | GAIAKAIGFP |
500:
WLMTIIGIID | ILFAPLCFFL | RSPPAKEEKM | AILMDHNCPI | KTKMYTQNNI |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Bovine
Human
Rat
ELISA Kit for Human Synaptic vesicular amine transporter
ELISA Kit for Human Synaptic vesicular amine transporter
ELISA Kit for Human Synaptic vesicular amine transporter
ELISA Kit for Human Synaptic vesicular amine transporter
CLIA Kit for Human Synaptic vesicular amine transporter
CLIA Kit for Human Synaptic vesicular amine transporter
CLIA Kit for Human Synaptic vesicular amine transporter
CLIA Kit for Human Synaptic vesicular amine transporter
Polyclonal Antibody for Human Synaptic vesicular amine transporter
Polyclonal Antibody for Human Synaptic vesicular amine transporter
Polyclonal Antibody for Human Synaptic vesicular amine transporter
Polyclonal Antibody for Human Synaptic vesicular amine transporter
Monoclonal Antibody for Human Synaptic vesicular amine transporter
Monoclonal Antibody for Human Synaptic vesicular amine transporter
Monoclonal Antibody for Human Synaptic vesicular amine transporter
Monoclonal Antibody for Human Synaptic vesicular amine transporter
Protein for Human Synaptic vesicular amine transporter
Protein for Human Synaptic vesicular amine transporter
Protein for Human Synaptic vesicular amine transporter
Protein for Human Synaptic vesicular amine transporter
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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"A human synaptic vesicle monoamine transporter cDNA predicts posttranslational modifications, reveals chromosome 10 gene localization and identifies TaqI RFLPs."
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Substantia nigra .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Brain .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.
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Nat. Genet.36:40-45(2004)
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Uterus .
7.
"The DNA sequence and comparative analysis of human chromosome 10."
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.
Mural R.J.
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more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISULFIDE BOND
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Platelet .